Intratumoral Bromelain + Acetylcysteine in Relapsed and Unresectable Pseudomyxoma Peritonei

Inclusion Criteria: * Pseudomyxoma peritonei diagnosis through imaging tests and/or histological studies * Pseudomyxoma peritonei relapse in abdominal area in patients who comply inoperability criteria, which are: At least two HIPEC operations or major abdominal surgery (PSS \> 3). Patients with acute morbidities (ASA score IV) * ECOG 0-2 * Age ≥ 18 * Signs informed consent Exclusion Criteria: * Candidates to other potentially healing treatments * Allergy to bromelains (pineapple), N-Acetylcysteine or possible cross-reactive allergy (eggs, sulphate. latex, carrots, celery, wheat...) * Non-manageable coagulation alterations * No possibility of intraabdominal drainage catheter * Acute respiratory pathology (asthma, COPD), acute hepatic, cardiopathic or kidney pathology * Allergy to any substance that might cause crossed reactivity to bromelain * Unwillingness to participate in this clinical trial