Robotic-assisted Versus Conventional Total Knee Arthroplasty

Inclusion Criteria: 1. Patient is age between 18 and 85 years old, inclusive; 2. Patient qualifies for a primary TKA based on the investigator's clinical judgement; 3. Patient is a candidate for commercially available Persona® Knee Joint Prosthese which is compatible with the ROSA® Knee System; 4. Patient is willing and able to provide written Informed Consent. Exclusion Criteria: 1. Patient planning to receive bilateral TKA surgery within 3 months; 2. Patient who has undergone revision surgery for partial or total knee arthroplasty of the ipsilateral knee； 3. Bone tumor patient who has undergone bilateral TKA; 4. Stable, painless ipsilateral knee arthrodesis within a satisfactory function and position; 5. Patient who has received partial or total knee arthroplasty for the contralateral knee within 6 months prior to scheduled primary TKA; 6. Patient has active, local infection or previous intra-articular infection in the affected joint; 7. Insufficient bone stock on femoral or tibial surfaces; 8. Skeletal immaturity; 9. Osteomalacia or any metabolic disorder which may impair bone formation; 10. Patient has neurologic disorders (e.g. Stroke); 11. Patient hs diseases that could lead to prosthesis instability, failure of prosthesis fixation or postoperative complications (e.g. Arthrodesis, Scoliosis, Lumbar Stenosis) 12. Patient has a hip pathology with significant bone loss (e.g. avascular necrosis of the femoral head with collapse, severe dysplasia of the femoral head or the acetabulum); 13. Patient has hip pathology severely limiting range of motion (e.g. arthrodesis, severe contractures, chronic severe dislocation); 14. Patients with severe knee instability caused by incomplete collateral ligaments, cruciate ligaments, and posterolateral structural injury; 15. Rheumatoid arthritis accompanied by an ulcer of the skin or history of recurrent breakdown of the skin; 16. Patient has severe angular knee deformity of \>20° varus or \>20° valgus; 17. Patient has a known or suspected sensitivity or allergy to one or more of the implant materials; 18. Patient has other contraindications specified by the implant manufacturer; 19. Patient is pregnant or considered a member of a protected population (e.g. prisoner, mentally incompetent); 20. In the past 1 month participated in or is participating in clinical trials related to other drugs and medical devices; 21. Any other conditions that the investigator considers inappropriate for participation in this trial.