HFNC and Prone Positioning in Awake Patients With Severe COVID-19

Hôpital Universitaire Fattouma Bourguiba120 enrolled

Overview

The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.

The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF. All patients with ARF related to Covid-19 and admitted to the ICU are turned in prone position whenever tolerated, while receiving oxygenation with HFNC. Outcomes of interest are the rate of success or failure (defined as the need for intubation and mechanical ventilation)

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Hypoxemic Respiratory Failure

Interventions

prone positionPROCEDURE

patients are returned from prone to supine position while receiving oxygenation through HFNC

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * aged ≥18 years, admitted to the medical ICU for confirmed Covid-19 and acute hypoxemic respiratory failure Exclusion Criteria: * patients already intubated at admission or those requiring immediate intubation

Locations (1)

CHU F.Bourguiba

Monastir, Tunisia

Outcomes

Primary Outcomes

Number of patients without intubation

successful oxygenation without intubation

Time frame: through study completion, an average of 28 days

Data from ClinicalTrials.gov

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