Acoart SCB SFA: Sirolimus Coated Balloon Catheter in the Treatment of Femoropopliteal Artery Stenosis

Inclusion Criteria: * Age ≥18 years old and ≤80 years old * Had lower extremity arterial occlusive diseases, and Rutherford classification is 2-5 * SFA and/or popliteal artery had severe stenosis (stenosis degree ≥70%) or occlusion. * The length of target lesion less than 20 cm * Subject (or legal guardian) understands the study requirements and procedures and provides written Informed Consent before any study tests or procedures are performed Exclusion Criteria: * The plasma creatinine level is higher than 150 umol/L * Thrombolysis or thrombectomy is required * There are more than 2 lesion need to treat in the target vessel. * The patient had underwent lower-limb arterial surgery or thrombolysis on the target limb within 6 weeks. * The target lesion had residual stenosis\>30% or flow-limit dissection after pre-dilatation. * The patient had outflow less than 1 vessel * The lesion located in a stent. * Patient has a known allergy to aspirin, clopidogrel, heparin, paclitaxel, sirolimus or contrast medium that cannot be adequately pre-medicated. * Women who are pregnant or breast-feeding. * The subjects have participated in other drug property studies or device studies that have not yet completed the main end point. * Patient has life expectancy of less than 12 months. * The investigator think the patient is not suitable for participation in the clinical trial.