The Safety, Tolerability, Pharmacokinetic, Food Effect Study and the interaction with Oseltamivir Phosphate Capsules of HEC116094 in Healthy Subjects
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
118
Part B:Mulltiple doses up to 5 days; Part C:Each cycle was administered for 5 days
The Shanghai xuhui district central hospital
Shanghai, Shanghai Municipality, China
Safety and Tolerability of HEC116094 by Assessment of the Number of Adverse
To investigate the safety and tolerability of HEC116094 by assessment of AEs
Time frame: up to 7 days at Part A and 11 days at Part B and 26 days at Part C
Cmax
Maximum Plasma Concentration(Cmax)of HEC116094
Time frame: up to 72 hours
AUC
Area Under the Curve(AUC) of HEC116094
Time frame: up to 72 hours
Tmax
Maximum Peak Time(Tmax) of HEC116094
Time frame: up to 72 hours
T1/2
Maximum Peak Time(Tmax) of HEC116094
Time frame: up to 72 hours
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