Clinical Study on the Effectiveness and Safety Evaluation of Directional Atherectomy Combined With Drug-coated Balloons

Inclusion Criteria: * Age over 18 years old * Ruthford grade 2-5 patients * For patients whose arteries in both lower extremities meet the enrollment criteria, both lower extremities can be included * At least one outflow tract over 10 cm at the distal end of the knee is continuous with a healthy back of the foot or internal and external arteries of the plantar * The guide wire clearly passed through the lesion and the follow-up treatment was performed. In the case of failed anterograde passage, reverse puncture to achieve the guide wire through the lesion can also be included in the group * After the failure of the first intracavitary treatment, the blood vessel can be recanalized by the intracavitary treatment again, and it can still be included in the group * Patients with aortic iliac artery disease can be included in the group after the aortic artery is opened * Patients who are willing to participate in this study and sign informed consent * For severely infected R6 patients, if the infection is effectively controlled, they can be considered for inclusion Exclusion Criteria: * Patients who refuse to participate in this observational study * Femoral popliteal artery disease with acute and subacute thrombosis * Patients with thromboangiitis * Patients who have failed endovascular treatment and transferred to surgical treatment * For patients who have received plaque exfoliation on the femoral artery * Patients who are allergic to heparin, low molecular weight heparin and contrast agents * Patients enrolled in other clinical studies in the past 3 months * Pregnant women * Patients who have a life span of less than 2 years due to serious diseases