The patients who had COVID-19 infection, and after that reported for one of the signs of gastrointestinal disorder (esophageal and anorectal) will be underwent to esophageal and anorectal motor monitoring investigation (HRM manometry) on standard protocol.
The patients who had COVID-19 infection, and after that reported for one of the signs of gastrointestinal (esophageal and anorectal disorder) will be underwent to esophageal and anorectal motor monitoring investigation (HRM manometry) on standard protocol. The patients with dysphagia, chest discomfort during swallowing, or chest pain during swallowing, patients with obstipation, fecal evacuation symptoms, lower stomach discomfort before defecation etc. will be included in the study. In all of them other gastrointestinal diseases will be excluded by standard routine laboratory investigation, ultrasound, routine endoscopy investigation and 24 hours impedance pH-measurement. After manometric measurement of esophagus and anorectal region to standard protocol by using MMS-HRM 360 monitoring system with 36 canals catheter for esophagus and 24 canals catheter for anorectal monitoring, data will be calculated by using statistics.
Study Type
OBSERVATIONAL
Enrollment
120
Prof.dr.sc. Žarko Babić, FEBGH
Zagreb, Select State, Croatia
RECRUITINGMeasurement of esophageal parameters 1 on manometry
In esophagus we will measure Upper and lower esophageal sphincter pressure in mmHg.
Time frame: 120 days
Measurement of esophageal parameters 2 on manometry
In esophagus we will measure Integrated relaxation pressure (IRP) in mmHg.
Time frame: 120 days
Measurement of esophageal parameters 3 on manometry
In esophagus we will measure Contractile front velocity (CVF) in cm/s.
Time frame: 120 days
Measurement of esophageal parameters 4 on manometry
In esophagus we will measure Distal contractile integral (DCI) in mmHg.s.cm.
Time frame: 120 days
Measurement of esophageal parameters 5 on manometry
In esophagus we will measure Distal latency (DL) in seconds.
Time frame: 120 days
Measurement of esophageal parameters 6 on manometry
In esophagus we will measure Peristaltic brake (BR) in cm.
Time frame: 120 days
Measurement of anorectal parameters 1 on manometry
On anorectal manometry we will measure Resting test pressure in mmHg.
Time frame: 2 years
Measurement of anorectal parameters 2 on manometry
On anorectal manometry we will measure Squeeze test pressure in mmHg.
Time frame: 2 years
Measurement of anorectal parameters 3 on manometry
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
On anorectal manometry we will measure Endurance squeeze test pressure in mmHg.
Time frame: 2 years
Measurement of anorectal parameters 4 on manometry
On anorectal manometry we will measure recto-anal inhibitory reflex test (RAIR)- relaxation in percent.
Time frame: 2 years
Measurement of anorectal parameters 5 on manometry
On anorectal manometry we will measure Push test pressure in mmHg.
Time frame: 2 years
Measurement of anorectal parameters 6 on manometry
On anorectal manometry we will measure Sensation test with ml in balloon.
Time frame: 2 years
Measurement of anorectal parameters 7 on manometry
On anorectal manometry we will measure Balloon expulsion test as positive or negative.
Time frame: 2 years