Femoral acetabular impingement (FAI) is a common disease of the hip joint. In this study, whole-genome sequencing was used to further explore the pathogenesis of this disease.
Femoral acetabular impingement (FAI) is a group of chronic hip pain caused by the impact between the proximal femur and the edge of the acetabulum due to the anatomical abnormality of the hip joint, which damages the labrum and adjacent cartilage, and causes limited hip movement, especially limited flexion and internal rotation. However, the specific etiology of FAI is still unknown at present. The application of genome-wide, exon and transcription research methods to the study of hip impaction syndrome can uncover key differentially expressed genes and provide a theoretical basis for the study of FAI.
Study Type
OBSERVATIONAL
Enrollment
100
Exposures
Peking University Third Hospital
Beijing, China
The patients were clinically diagnosed with FAI (femoral acetabular impingement) and underwent arthroscopic surgery, then clinical samples were collected.
Peripheral blood from 100 patients with femoral acetabular impingement syndrome was collected and DNA was extracted.
Time frame: The patient was diagnosed with FAI, and conservative treatment was ineffective for an average of 6 months.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.