AS-OCT Study in Diabetic Retinopathy

Federico II University30 enrolled

Overview

This study evaluates the corneal features using anterior segment - optical coherence tomography in patients affected by type 2 diabetes mellitus

To investigate the potential role of anterior segment-optical coherence tomography (AS-OCT) in identifying the corneal changes (in particular in total corneal, epithelial and stromal thicknesses) in patients affected by type 2 diabetes mellitus, without signs of diabetic retinopathy at fundus examination. The AS-OCT could represents a valid early biomarker in these patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diabetes Mellitus

Interventions

Anterior segment-optical coherence tomographyDIAGNOSTIC_TEST

Each subject underwent anterior segment -optical coherence tomography to evaluate the total corneal, epthelium and stromal thicknesses.

Eligibility

Sex: ALLMin age: 50 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age older than 50 years * diagnosis of previous type 2 diabetes mellitus * absence of signs of diabetic retinopathy * absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * absence of significant lens opacities, low-quality OCT and OCT-A images Exclusion Criteria: * age younger than 50 years * absence of previous diagnosis of type 2 diabetes mellitus * presence of signs of diabetic retinopathy * presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * presence of significant lens opacities, low-quality OCT and OCT-A images.

Locations (1)

University of Naples "Federico II"

Naples, Italy

Outcomes

Primary Outcomes

The measurements of corneal features in patients with type 2 diabetes mellitus, using anterior segment-optical coherence tomography

The parameters analyzed by anterior segment-optical coherence tomography angiography were: total corneal, epithelial and stromal thicknesses

Time frame: twelve months

Data from ClinicalTrials.gov

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