The objective of our study is to evaluate the effect of CPAP on umbilical cord acid base status in morbidly obese women at the time of scheduled cesarean delivery. We hypothesize that neonates born to mothers wearing CPAP during the cesarean section will have a higher umbilical artery pH.
This is a randomized control trial comparing CPAP to routine airway management in morbidly obese patients undergoing scheduled cesarean delivery. Morbidly obese women meeting criteria for inclusion will be approached for participation. Women who are scheduled for cesarean delivery at Sentara Norfolk General Hospital will be approached at a prenatal appointment prior to scheduled date of delivery. If a woman agrees to participate in the study, she will be counseled and consented at that time.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
66
CPAP is a form of noninvasive positive pressure ventilation (NPPV). CPAP works to maintain adequate levels of PO2 and PCO2 through improved alveolar ventilation and maintenance of upper-airway patency.
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Eastern Virginia Medical School
Norfolk, Virginia, United States
Umbilical Cord Arterial pH
We hypothesize that neonates born to mothers wearing CPAP during the cesarean section will have a higher umbilical artery pH.
Time frame: At delivery
Patient satisfaction with use of CPAP
Survey will be used to determine patient experience and satisfaction
Time frame: Within 4 days following delivery (prior to discharge from hospital)
Effect of CPAP on maternal acid base status with analysis of venous blood gas
Maternal venous blood gas will be analyzed at the time of uterine incision to measure the acid base status
Time frame: At time of uterine incision
Effect of maternal CPAP use on neonatal Apgar scores
Apgar scores will be compared between 2 groups
Time frame: At delivery
Effect of maternal CPAP use on composite neonatal outcome
Perinatal death, respiratory support, Apgar score \<=3 at 5 min, hypoxic ischemic encephalopathy, hypotension requiring vasopressor support
Time frame: At delivery
Effect of duration in supine position prior to delivery on neonatal acid base status
Neonatal venous blood gas will be analyzed to determine the acid base status as it correlates to length of time in maternal supine position
Time frame: At delivery
Effect of duration in supine position prior to delivery on maternal acid base status
Maternal venous blood gas will be analyzed to determine the acid base status as it correlates to length of time in supine position
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Time frame: At delivery