Efficacy Testing of Collagen Peptide Drink

N/ACompletedNCT04996043

TCI Co., Ltd.60 enrolled

Overview

To assess Collagen Peptide Drink on skin condition improvement

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Enrollment

Conditions

Skin Condition

Interventions

Collagen Peptide DrinkDIETARY_SUPPLEMENT

Testing product

Placebo drinkDIETARY_SUPPLEMENT

Blank

Eligibility

Sex: ALLMin age: 20 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy adults aged above 20 years old Exclusion Criteria: * Subject who is not willing to participate in this study. * Patients with diseases of the skin, liver, kidney. * Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder. * Female who is pregnant or nursing or planning to become pregnant during the course of the study. * Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks. * Constant drug use * Participated cosmetic product human study in the past 3 months.

Locations (1)

Chia Nan University of Pharmacy ＆ Science

Tainan, Taiwan

Outcomes

Primary Outcomes

The change of skin wrinkles

VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units

Time frame: Change from Baseline skin wrinkles at 4 weeks

The change of skin texture

VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

Time frame: Change from Baseline skin texture at 4 weeks

The change of skin collagen density

DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units

Time frame: Change from Baseline skin collagen density at 4 weeks

The change of skin elasticity

Soft Plus was utilized to measure skin elasticity. Units: arbitrary units

Time frame: Change from Baseline skin elasticity at 4 weeks

The change of MMP-1 of blood

Venous blood was sampled to measure MMP-1

Time frame: Change from Baseline MMP-1 at 4 weeks

The change of TIMP-1 of blood

Venous blood was sampled to measure TIMP-1

Time frame: Change from Baseline TIMP-1 at 4 weeks

Secondary Outcomes

The change of skin melanin index

Soft Plus was utilized to measure skin melanin index. Units: arbitrary units

Time frame: Change from Baseline skin melanin index at 4 weeks

The change of skin L* value

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.

Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100

Time frame: Change from Baseline L* value at 4 weeks

The change of skin spots

VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units

Time frame: Change from Baseline skin spots at 4 weeks

The change of skin UV spots

VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units

Time frame: Change from Baseline skin UV spots at 4 weeks

The change of skin brown spots

VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units

Time frame: Change from Baseline skin brown spots at 4 weeks

The change of TNF-α of blood

Venous blood was sampled to measure TNF-α

Time frame: Change from Baseline TNF-α at 4 weeks

The change of IL-10 of blood

Venous blood was sampled to measure IL-10

Time frame: Change from Baseline IL-10 at 4 weeks

The change of SOD-RBC of blood

Venous blood was sampled to measure SOD-RBC

Time frame: Change from Baseline SOD-RBC at 4 weeks

The change of f-thiols of blood

Venous blood was sampled to measure f-thiols

Time frame: Change from Baseline f-thiols at 4 weeks

The change of t-GSH of blood

Venous blood was sampled to measure t-GSH

Time frame: Change from Baseline t-GSH at 4 weeks

The change of GST-RBC of blood

Venous blood was sampled to measure GST-RBC

Time frame: Change from Baseline GST-RBC at 4 weeks

The change of MDA of blood

Venous blood was sampled to measure MDA

Time frame: Change from Baseline MDA at 4 weeks

The change of skin moisture

Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120

Time frame: Change from Baseline skin moisture at 4 weeks

The change of blood total antioxidant capacity (TAC)

Venous blood was sampled to measure concentrations of TAC

Time frame: Change from Baseline TAC at 4 weeks