Catheterless Water Vapor Therapy for the Treatment of BPH

Inclusion Criteria: * Male subject of 40 - 80 years of age * Has provided informed consent * Has a diagnosis of bladder outlet obstruction due to benign prostatic enlargement * Able to complete self-administered questionnaires * Is a surgical candidate for Rezum * Has medical record documentation of Qmax \< 15 ml/s * Has medical record documentation of prostate volume from 30-80 ml by transrectal ultrasound (TRUS) * Has a bladder contractility index score ≥ 100, calculated by detrusor pressure at Qmax (pDet@qmax) + (5xQmax). * Willing to undergo pressure-flow studies to calculate BCI prior to surgical intervention. * Has serum creatinine within the normal range. * Able to perform intermittent catheterization. Exclusion Criteria: * Has a life expectancy \< 2 years * Is currently enrolled in or plans to enroll in any concurrent drug or device study * Has an active infection (e.g., urinary tract infection or prostatitis) * Has a diagnosis of or has received treatment for chronic prostatitis or chronic pelvic pain syndrome (e.g., nonbacterial chronic prostatitis) * Has been diagnosed with a urethral stricture or bladder neck contracture within the last 180 days * Has been diagnosed with 2 or more urethral strictures and/or bladder neck contractures within 5 years * Has a diagnosis of lichen sclerosis * Has a diagnosis of neurogenic bladder or other neurologic disorder that affects bladder function * Has a diagnosis of polyneuropathy (e.g., diabetic) * Has a history of lower urinary tract surgery * Has a diagnosis of stress urinary incontinence that requires treatment or daily pad or device use * Has an inability to perform intermittent self-catheterization * Has been catheterized or has a post-void residual (PVR) of \> 400 ml in the 14 days prior to the surgical procedure * Has a current diagnosis of bladder stones