SADBE for Congenital Melanocytic Nevi

Inclusion Criteria: * 18 years of age or older. * Subject or parents willing and able to give informed consent, and assent as appropriate. * Patients who have a clinical diagnosis of CMN with plans for elective non-urgent excision of part or all of their nevus, with nevus surface area of \> 6 cm2. Exclusion Criteria: * Immunosuppressive therapy with glucocorticoid or other systemic immunosuppressant within 4 weeks of recruitment (except for inhaled corticosteroids for asthma). * History of malignancy. * History of organ transplantation. * Known immunosuppressive disease, including infection with HIV. * Severe medical comorbidities (diabetes mellitus requiring insulin, CHF of any severity, MI, CVA, or TIA within 3 months of screening visit, unstable angina pectoris, oxygen-dependent severe pulmonary disease) * Subject is currently enrolled in another investigational device or drug trial(s), or subject has received other investigational agent(s) within 28 days of baseline visit. * Subjects who have known hypersensitivity to SADBE or any of its components. * Any condition judged by the investigator to cause this clinical trial to be detrimental to the patient.