Observation of the Effects of Guideline-driven Lifestyle Interventions, Including Use of a Red-yeast Based Nutraceutical

Inclusion Criteria: * Age between 25 and 75 years; * In primary prevention for low-moderate CV risk, with diet and physical exercise to control raised LDL-C level, for at least 3 months; * LDL-C \> 100 mg/dL (2.6 mmol/L), \< 190 mg/dL (4.9 mmol/L) * CV risk SCORE \<5% (based on SCORE chart according to figure I for Poland respective figure 2 for Austria and Germany in the ESC/EAS guideline 2019); * Triglyceride \<400 mg/dL; * Advised to use nutraceutical as part of the lifestyle intervention as per guideline and within the product label (i.e. posology as in product label); * Written informed consent. Exclusion Criteria: * Subjects being treated or who have been treated for up to 3 months before the start of the study with lipid-lowering drugs or nutraceuticals including functional foods for which lipid-lowering effects are known (e.g. fish oil, sterol-containing yoghurts etc.); * Subjects involved in other clinical studies with pharmaceutical products * Known laboratory evidence of either liver, muscle, thyroid or kidney dysfunction; * Subjects with prior history of cardiovascular events or with high cardiovascular risk equivalents; * Uncontrolled hypertension (systolic blood pressure \>190 mmHg or diastolic blood pressure \>100 mmHg); * Pregnancy and breastfeeding.