Effect of Different Biomimetic Materials on White Spot Lesions in Enamel

Benha University21 enrolled

Overview

This study will be conducted to evaluate: 1- The remineralizing effect of different biomimetic materials (Zinc carbonate hydroxyapatite nanoparticles, Poly-amido amine (PAMAM) and bioactive glass nanoparticles) on white spot lesions in enamel. 2- The clinical efficacy of these agents on disappearance of these white spots.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

White Spot Lesion

Interventions

Time of assessmentOTHER

Immediate and after one month and after two months

Eligibility

Sex: ALLMin age: 15 YearsMax age: 25 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Total of 21 patients enrolled in this study will be selected having at least 4 teeth (one on each quadrant) which will be extracted for orthodontic treatment. * These patients will be selected according to age groups between 15-25 years old * good oral hygiene * free of destroying habits for dental tissues Exclusion Criteria: * Bruxism * soft drinks consumption * acid regurgitation, etc.). * Selected teeth having any cracks, malformations, dysplasia or caries.

Locations (1)

Faculty of dental medicine for girls branch of Alazhar University

Cairo, Egypt

Outcomes

Primary Outcomes

change in remineralization from base line to time limit

Change in its density in digital xray

Time frame: Immediate and one month and two months

changes of appearance from base line photograph to time limit

White spots disappear on digital photography

Time frame: Immediate and one month and two months

Data from ClinicalTrials.gov

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