A retrospective cohort study to explore the association between clinical pharmacists' interventions and antibiotic consumption through the use of the medical electronic reports and to identify mortality and cost savings in hospital infectious disease.
The role of clinical pharmacist includes : 1. a check of suitable selection and dosing of antimicrobials according to the diagnosis, type of infection, antimicrobial cultures as possible, comorbidities of patients (renal or hepatic function, etc), adverse effect, and drug interaction with other drugs. 2. Documentation of the clinical intervention, cost-saving, adverse effect,, antimicrobial culture and antimicrobial consumption on the electronic program (CPC "clinical patient care"). 3. The clinical pharmacist inspector reviews the data recorded on CPC.
Study Type
OBSERVATIONAL
Enrollment
2,601
There is no intervention
Ministers of health
Alexandria, Egypt
Antimicrobial consumption
consumption of antimicrobials (defined daily doses / 100 patient-days)
Time frame: 2 years
Days of therapy (DOT)
Number of days of each antimicrobial received for therapy
Time frame: 2 years
Length of therapy(LOT)
The number of days a patient takes an antibacterial drug, regardless of the number of different medications
Time frame: 2 years
cost savings
(initial treatment cost × days before intervention) - (cost after intervention × days with this treatment),
Time frame: 2 years
Mortality rate
in-hospital mortality rate (%)
Time frame: 2 years
Antimicrobial resistance
resistance defined as resistance to at least one antimicrobial from the panel for all organisms, and for a subset of organisms belonging to the ESKAPE group (Enterococcus faecium, S. aureus, Klebsiella pneumonia, Acinetobacter baumannii, Pseudomonas aeruginosa , and Enterobacter spp.
Time frame: 2 years
The incidence of adverse reaction of antimicrobial
An unexpected medical problem that happens during treatment with antimicrobial.
Time frame: 2 years
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