Follow-up study of Coronavirus disease 2019 (COVID-19) survivors has rarely been reported. We aimed to investigate longitudinal changes in the characteristics of COVID-19 survivors after discharge.
From December 2019, coronavirus disease 2019 (COVID-19), caused by a β-coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread across the globe. Numerous studies have been performed so far to investigate clinical characteristics, risk factors, potential treatment and pathogenesis of COVID-19. However, little information is available on the long-term prognosis and possible sequelae of COVID-19 survivors who have recovered and been discharged from hospital. Hence, the investigators conducted a prospective study to investigate the long-time prognosis and the possible sequelae of COVID-19 survivors. The investigators evaluated Demographic and clinical characteristics, laboratory and radiological findings,pulmonary function tests, electrocardiogram, complications as well as treatment and symptoms and signs of COVID-19 patients.
Study Type
OBSERVATIONAL
Enrollment
1,000
Department of infectious disease, Tongji Hospital
Wuhan, Hubei, China
symptoms and signs
symptoms and signs will be collected.
Time frame: 1-3years
SF-36 Questionnaire to the ability of Life
Quality of Life will be assesed using the MOS item short from health survey（SF-36.Minimum value:0, Maximum value: 100. Higher scores mean a better outcome.
Time frame: 1-3years
Mental quality
Mental quality will be assessed using hospital anxiety and depression scale.Minimum value:0, Maximum value: 21. Higher scores mean a worse outcome.
Time frame: 1-3years
laboratory findings,change from baseline for blood laboratory measures
the change from baseline for laboratory examination （Hb in g/L, Leukocyte in /L, neutrophil count in /L，lymphocyte count in /L，Platelet count in /L，Creatinine in μmol/L, Bilirubin in mg/dL, ALP in U/L, γ-glutamyl transpeptidase in U/L，AST in U/L, ALT in U/L, Albumin in g/dL, triglycerides in mmol/L, total cholesterol in mmol/L，cardiac troponin I in ng/mL， myoglobin in ng/mL， brain natriuretic peptide precursors in pg/mL， lactate dehydrogenase in U/L, Creatine Kinase in U/L).
Time frame: 1-3years
Radiological findings
Radiological findings such as chest computed tomography will be assessed.
Time frame: 1-3years
pulmonary function
pulmonary function tests will be assessed.
Time frame: 1-3years
Heart function
electrocardiogram including arrhythmia,ST-T change and conduction block will be assessed.（they have no Units）
Time frame: 1-3years
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Abdominal ultrasound
Abdominal ultrasound will be assessed.
Time frame: 1-3years