Effect of Frankincense Extract Gel on Non-Surgical Treatment of Chronic Periodontitis

Tanta University20 enrolled

Overview

This study will evaluate the effect of the subgingival application of Frankincense extract gel as an adjunct to scaling and root planning (SRP) in chronic periodontitis.

: twenty patients will be randomly selected and equally divided into Group I: will receive SRP only, group II: will receive SRP and Frankincense extract the gel. Subgingival application of Frankincense extract gel will be performed following initial SRP )day 1) and at 7, and 14 days. Clinical measurements included pocket depth (PD), bleeding on probing (BOP), and clinical attachment level (CAL). Real-time PCR was carried out to determine the effect of the treatment on Porphyromonas gingivalis (Pg). Clinical measurements and Plaque samples for PCR were recorded at baseline (before treatment), one, and three months after treatment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Chronic Periodontitis

Interventions

scaling and root planingPROCEDURE

will receive scaling and root planing only

Frankincense extract gel natural herbal productPROCEDURE

will receive Scaling and root planing then. Subgingival application of Frankincense extract gel

Eligibility

Sex: ALLMin age: 30 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * systemically healthy patients were selected * patients who had not received any medications for the previous six months that may interfere with periodontal tissue health or healing. * Patients should demonstrate their ability to maintain good oral hygiene Exclusion Criteria: * Smokers and pregnant patients. * Medically compromised patients and systemic conditions precluding periodontal surgery.

Locations (1)

Doaa Ahmed yousef bayoumi

Tanta, Gharbia Governorate, Egypt

Outcomes

Primary Outcomes

probing pocket depth

probing pocket depth will be recorded at baseline, at site that will be treated

Time frame: baseline

probing pocket depth

probing pocket depth will be recorded at 1 month at the site to be treated

Time frame: 1 month

probing pocket depth

probing pocket depth will be recorded at 3 month at the site to be treated

Time frame: 3 month

clinical attachment level

clinical attachment level will be recorded at baseline,

Time frame: baseline

clinical attachment level

clinical attachment level will be recorded at , 1 month at the site to be treated

Time frame: 1 month

clinical attachment level

clinical attachment level will be recorded at 3 months at the site to be treated

Time frame: 3 month

bleeding on probing

bleeding on probingwill be recorded at baseline, at the site to be treated

Time frame: baseline

bleeding on probing

bleeding on probingwill be recorded at 1, month at the site to be treated

Time frame: 1 month

bleeding on probing

bleeding on probingwill be recorded at 3 months at the site to be treated

Time frame: 3 month

Data from ClinicalTrials.gov

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