This study is aimed to investigate the treatment vitamin D3 as complementary therapy with routine care for early mild symptoms of COVID-19 in outpatients setting.
There is currently no specific early-stage therapeutic treatment available for COVID-19. Vitamin D3 is a strong antioxidant, and anti-inflammatory/immunomodulatory agent. The present study is aimed to investigate the treatment benefits of vitamin D3 as add-on therapy to the routine care for early mild symptoms of COVID-19 infection in outpatients setting.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
50
Standard of care treatment as per the hospital guidelines
A daily dose of 5000 IU vitamin D3 for 7 days.
Ayub Teaching Hospital
Abbottabad, Khyber Pakhtunkhwa, Pakistan
SARS-CoV-2 Negativity by RT-PCR
The numbers of patients that tests COVID-19 negative
Time frame: From day 1 to day 14
COVID-19 symptoms improvement
The numbers of patients whose COVID-19 symptoms are subsided
Time frame: From day 1 to day 14
Changes in CRP level
Improvement in blood CRP level
Time frame: From day 1 to day 14
Changes in D-dimer level
Improvement in blood D-dimer level
Time frame: From day 1 to day 14
Changes in LDH level
Improvement in blood LDH level
Time frame: From day 1 to day 14
Changes in ferritin level
Improvement in blood ferritin level
Time frame: From day 1 to day 14
Changes in full blood count
Improvement in full blood count
Time frame: From day 1 to day 14
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