Efficacy and Safety of Metoprolol Tartrate Tablets Combined With Chinese Traditional Medicine on Premature Ventricular Complex.

Inclusion Criteria: * Lown PVC grade, II-IVA; * in patients with coronary heart disease and comorbid PVC or non-organic heart disease, the PVC frequency was 3000-30000 times/24 h; * New York Heart Association grade, I or II; * ejection fraction, ≥45%; * written informed consent to participate in the trial. Exclusion Criteria: * presence of bradyarrhythmia (\<50 beats/min), including sinus syndrome and atrioventricular block (second or third degree atrioventricular block); * presence of persistent ventricular tachycardia, non-persistent ventricular tachycardia, and/or persistent atrial fibrillation; * presence of severe PVC requiring treatment with other antiarrhythmic drugs; -presence of drug-induced, electrolyte-induced, or acid-base-induced arrhythmia; * presence of uncontrolled or severe hypertension (e.g., grade ≥3 hypertension); * presence of uncontrolled diabetes; presence of alanine aminotransferase or aspartate aminotransferase level ≥1.5-fold above the upper limit of normal, urea nitrogen level ≥1.2-fold above the upper limit of normal, and/or blood creatinine above the upper limit of normal; * presence of severe respiratory dysfunction or asthma; * presence of primary hematopoietic diseases, other systemic diseases (e.g., hyperthyroidism), poor peripheral circulation perfusion, severe peripheral vascular diseases, and/or PVC with unknown etiology; * presence of allergic constitution, mental disorder, alcoholism, and/or smoking habit; * pregnancy or lactation; * ongoing β-blocker treatment or contraindications to β-blocker treatment; -participation in other clinical trials within the prior 3 months; * and other reasons for lack of suitability to participate in this study, as determined by the investigators.