Effect of Dexamethasone as Analgesic Treatment After Total Knee Arthroplasty: Subgroup Analyses of The DEX-2-TKA Randomized Clinical Trial This explorative post-hoc analysis is a substudy of the DEX-2-TKA-trial (NCT03506789) investigating diffefferent subgroups of the patients included in the main trial.
Effect of Dexamethasone as Analgesic Treatment After Total Knee Arthroplasty: Subgroup Analyses of The DEX-2-TKA Randomized Clinical Trial This explorative post-hoc analysis is a substudy of the DEX-2-TKA-trial (NCT03506789) investigating diffefferent subgroups of the patients included in the main trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
485
24 mg intravenous Dexamethasone (6 ml)
6 ml of isotonic saline
Gildhøj Privathospital
Brøndby, Denmark
Bispebjerg Hospital
Copenhagen, Denmark
Sjællands Universitetshospital, Køge
Køge, Denmark
Næstsved Sygehus
Næstved, Denmark
Odense Universitetshospital
Cumulative usage of morphine 0-48 hours postoperatively
Morphine administered both as patient-controlled analgesia (PCA) i.v. morphine 0-24 hours and oral morphine on demand 24-48 hours, and any other supplemental morphine administered postoperatively. Consumption in mg
Time frame: Time Frame: 0-48 hours postoperatively
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Odense, Denmark