Comparative Study Using Negative Pressure Dressing With & Without Silver Alginate to Promote Healing in Chronic Wounds.

Dow University of Health Sciences62 enrolled

Overview

The randomized control trial will be conducted in the Department of Plastic and Reconstructive Surgery at Dr. Ruth K.M. Pfau Civil Hospital Karachi.General population admitted in Civil Hospital Karachi, for wound coverage with skin grafting meetimg inclusion criteria will be included.

Wound will be covered with negative pressure dressings that are composed of a sterile foam dressing surrounded by an occlusive film that adheres to the nearby, normal skin. Suction is applied to the dressing and a draining tube connect to a wall fixed assisted vacuum canister. Patients will be provided with paper chits with A or B marked on it. Patients picking up A chit will be dealt as A group where wound will be covered with VAC dressings only where by patients picking up B chit will be dealt as B group where wound will be covered with a single layer of Ag+ hydrocolloid dressings. Such pattern of dressing will be followed in every change of dressing in 48 hours. The wound site will be photographed after every change of dressings. The wound site will be photographically monitored by a team of plastic surgeons to assess granulation tissue, by noting the size of wound, color and shine of granulation tissue and edema.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Wound Healing

Interventions

silver alginateOTHER

silver alginate hydrofiber dressing

VAC dressing without silver alginateOTHER

vaccum assisted dressing

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Both genders above 18 years * Wounds for more than 6 weeks * History of trauma, tumor, congenital physical abnormalities * Hemoglobin levels more than 10 g/dl * Platelet count above 150 x 10E9/L * Size of wound \> 10\*10cm. Exclusion Criteria: * Pressure ulcers * Co-morbidities like diabetes or hypertension * Bleeding vessels * Presence of Necrotic tissue * Malignancy in wounds

Locations (1)

Mahak

Karachi, Sindh, Pakistan

Outcomes

Primary Outcomes

Granulation tissue

The wound site will be photographically monitored by a team of plastic surgeons to assess granulation tissue, by noting the size of wound, color and shine of granulation tissue and edema and also by questionnare fillled by patient.

Time frame: 6 days

size of wound.

he wound site will be photographically monitored by a team of plastic surgeons to assess granulation tissue, by noting the size of wound, color and shine of granulation tissue and edema and also by questionnare fillled by patient.

Time frame: 6 days

Data from ClinicalTrials.gov

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