The aim of this study is to use a tea-based mouthwash to relieve pain and discomfort in patients with stomatitis and ulcers.
The objective of this study is to use tea as a base, supplemented with licorice to reduce bitterness and astringency, to make mouthwash, and use tea's antioxidant and anti-inflammatory properties to relieve the pain and discomfort of stomatitis and ulcer patients. This study will observe the difference between saliva and oral mucosal cells before and after treatment, to find the mechanism of effective treatment of stomatitis.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Using tea as a base, supplemented with licorice to make mouthwash to relieve stomatitis.
Chiayi chang Gung Memorial Hospital
Chiayi City, Taiwan
Xerostomia questionnaire (XQ)
Questionnaires for symptoms relief of dry mouth
Time frame: 4 weeks
Xerostomia Inventory (XI)
A multi-item approach to measuring dry mouth
Time frame: 4 weeks
Rate of oral mucosa cells with angiotensin-converting enzyme 2 (ACE2) staining (+)
Immunohistochemistry stain for ACE2 protein
Time frame: 4 weeks
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