CD147-CAR T Cells for Relapsed/Refractory T Cell Non-Hodgkin's Lymphoma

Inclusion Criteria: * The subject must meet all of the following criteria: 1. 18-65 years old; 2. Relapsed or refractory T-NHLs, including peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), angioimmunoblastic T-cell lymphoma (AITL), ALK-positive ALCL, ALK-negative Image result for anaplastic large cell lymphoma (ALCL), enteropathy-related T-cell lymphoma, hepatosplenic T-cell lymphoma, etc.; 3. Previously received ≥2 lines of treatment without a complete response; 4. Immunohistochemical detection of tumor cells CD147 positive; 5. ECOG score 0-2; 6. The collection of mononuclear cells can be performed upon the judgment of the researcher; 7. No contraindications for allogeneic hematopoietic stem cell transplantation (AlloHCT); 8. Have donors for AlloHCT; 9. Agree for sequential treatment of AlloHCT; 10. Without serious organ dysfunction in 2 weeks before CAR-T infusion: 1. Heart: without arrhythmia, LVEF≥50%, and without pericardial effusion; without heart failure (NYHA class III or IV) within12 months before CAR-T infusion; without myocardial infarction within 12 months before CAR-T infusion; without long-QT syndrome or secondary QT interval prolongation; 2. Liver: ALT\<2 times the upper limit of normal (ULN) and TBIL\<1.5 times ULN, without active hepatitis; 3. APTT and PT\<1.5 times ULN; 4. Kidney: Serum creatinine \<1.5 mg/dl; or if the serum creatinine exceeds the upper limit, eGFR (CKD-EPI formula) needs to be \> 50 ml/min; 5. Fingertip blood oxygen saturation ≥ 92%. 11. Estimated survival ≥ 3 months; 12. Sexually active patients must be willing to use an effective method of birth control during the study period and within 6 months after the study ending, and male partners should use condoms; 13. The patient is willing to join this clinical trial and sign an informed consent. Exclusion Criteria: * Anyone who has one or more of the following: 1. A history of other malignancies with a disease-free period \< 5 years (except for cured basal cell carcinoma of the skin, cured cervical carcinoma in situ, and gastrointestinal tumors proven to be cured by endoscopic mucosal resection); 2. Those who have received allogeneic hematopoietic stem cell transplantation or organ transplantation; 3. Patients with bone marrow involvement; 4. Those who are allergic to the biological agents in CAR-T cell product ; 5. Pregnant or breastfeeding; 6. Active bacterial, fungal or viral infection; 7. Receiving systemic hormone therapy 1 week before participating in the clinical trial; 8. Have received other gene therapy before; 9. HBV or HCV infection or carrier is defined as: HBsAg positive or HBV-DNA positive; anti-HCV positive and HCV-RNA positive; 10. Active HIV infection; 11. Clinical diagnosis of virus infection or uncontrolled virus activation, including cytomegalovirus (CMV), adenovirus (ADV), BK virus or human herpesvirus 6 (HHV-6), etc.; 12. Central nervous system lymphoma (CNSL) is defined as the presence of ≥5 tumor cells/ ul in cerebrospinal fluid (CSF) or MRI suggested CNSL; any other CNS diseases, such as uncontrolled epilepsy, cerebral ischemia/hemorrhage, dementia, cerebellar disease or any autoimmune disease involving the central nervous system, or received treatment for central nervous system or brain metastasis (radiotherapy, surgery or other treatments); 13. Imaging determined lung infection; 14. Inappropriate to participate in the trial with investigators' decision.