This study investigates the neural mechanisms of cognitive function decline, cognitive assessment methods for subjects with mild cognitive dysfunction (Mild cognitive impairment, MCI, or cognitive decline milder than MCI), and the approaches used to improve and restore cognitive function.
Cognitive assessment tools are used to assess cognitive function of subjects in different cities. Functional and structural MRI and EEG are applied to investigate the neural mechanisms of cognitive function decline and effects of methods to improve and restore cognitive function.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
SINGLE
Enrollment
100
The Intervention group will be given recommended interventions tailored to individuals based on their risks (e.g., physical exercise programs, cognitive training, dietary advice, control of blood pressure and cholesterol, healthy diet, control obesity, stop smoking,reduce alcohol excess)
National Research Center for Rehabilitation Technical Aids
Beijing, Beijing Municipality, China
RECRUITINGChange in Cognitive function (SCD-9)
The SCD-9 questionnaire is used to assess cognitive function of participants.
Time frame: Change from Baseline Cognitive test results at 3 months.
Change in Cognitive function (MoCA)
The Montreal Cognitive Assessment test is used to assess cognitive function of participants.
Time frame: Change from Baseline Cognitive test results at 3 months.
Change in Cognitive function (AD8)
The AD8 test is used to assess cognitive function of participants.
Time frame: Change from Baseline Cognitive test results at 3 months.
Change in Cognitive function (CDR)
The Clinical Dementia Rating (CDR) test is used to assess cognitive function of participants.
Time frame: Change from Baseline Cognitive test results at 3 months.
Change in Physical capacity (TUG)
The timed up and go (TUG) test is used to evaluate physical capacity of participants.
Time frame: Change from Baseline physical capacity test results at 3 months.
Change in Physical capacity (chair standing)
The 30-second chair standing test is used to evaluate physical capacity of participants.
Time frame: Change from Baseline physical capacity test results at 3 months.
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