"In this study, the investigators plan to evaluate muscle mass and pain relief 4 weeks after performing epidural nerve block and Type I porcine atelocollagen injection into multifidus muscle in patients with chronic low back pain due to degenerative spinal disease for more than 6 months.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Epidural nerve block and atelocollagen injection into the multifidus muscle were performed sequentially. The target level is determined by the clinician by combining the pre-MRI and the patient's symptoms. All procedures are performed under the guidance of fluroscopy. For epidural nerve block, use 10cc of 0.9% normal saline mixed with 3000IU of hyaluronidase to be injected. After the epidural nerve block, a solution of 1 mL of atelocollagen mixed with 1 mL of 1% lidocaine is injected into the multifidus muscle to complete the entire procedure.
Ji Yeong Kim
Seoul, South Korea
cross-sectional area of the multifidus muscle
Changes in the cross-sectional area of the multifidus muscle at the 4th week of the intervention compared to before the intervention (measured value using ultrasound at outpatient).
Time frame: 28 days after atelocollagen injection
numeric rating score
numeric rating score, Score range from 0 to 100. Higher scores mean a worst outcome.
Time frame: 28 days after atelocollagen injection
oswestry disability index
oswestry disability index, Score range from 0 to 50. Higher scores mean a worst outcome.
Time frame: 28 days after atelocollagen injection
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