COVID-19 Vaccines in Patients With Chronic Liver Disease

Inclusion Criteria: * Age ≥ 18 years. * Serum ALT and AST are both ≤ 80 U/L. * HIV and TPHA screening were negative. * Body temperature ≤37.0℃. Exclusion Criteria: * Patients who confirmed the diagnosis of liver cancer by imaging examination (CT/MRI/B scan). * Patients who are allergic to any component of the vaccine, or have a serious history of vaccine allergy. * Women who is pregnant, breastfeeding, or planning to be pregnant within 6 months. * Patients with cardiovascular diseases, such as arrhythmia, conduction block, myocardial infarction, and severe hypertension can not be well controlled by drugs. * Patients with severe chronic diseases or diseases can not be controlled well during the progress, such as asthma, diabetes, thyroid disease, etc. Congenital or acquired angioedema / neuroedema.c. * Patients with urticaria within a year. * Patients with coagulation disorder. * Faintng during acupuncture treatment . * Patients who received other investigational drugs within one month. * Be receiving anti-TB treatment. * Other conditions determined by the researcher.