This study aim to describe hyperkalemia clinical burden and investigate the risk factors associated with the burden on HD facility level.
This study is an observational survey study. We estimate 300 hemodialysis (HD) centres will be enrolled in the study. Summarized data on serum potassium (sK) after long interdialytic interval (LIDI), facility practice pattern and patient characteristics which may be related with sK management, and death records information including number of deaths for each centre will be collected. All the data collected and analysed are on HD facility level, not on patient-level. We are aiming to describe hyperkalemia clinical burden and investigate the risk factors associated with the burden on HD facility level. Association between sK management and long-term outcome will also be explored.
Study Type
OBSERVATIONAL
Enrollment
300
Peking University People's Hospital
Beijing, Beijing Municipality, China
RECRUITINGTo investigate the risk factors associated with hyperkalemia clinical burden on HD facility level
Examine the association of risk factors at current status to hyperkalemia prevalence on HD facility level
Time frame: 3 years
To describe hyperkalemia clinical burden on HD facility level
Constitution ratio of different sK levels after LIDI in ranges: (0, 3.5\], (3.5, 5.0\], (5.0, 5.5\], (5.5, 6.0\], (6.0, 6.5\], (6.5, 7.0\], (7.0\~) mmol/L in HD centers
Time frame: 3 years
To describe sK management pattern on HD facility level
Proportion of patients on 3 times/week, 5 times/2 weeks, 2 times/week, less than 2 times/week, and other frequencies of HD treatment Proportion of patients with dialysate potassium concentration at 2.0 mmol/L, 2.5 mmol/L, 3.0 mmol/L and others Proportion of patients with sK testing on monthly, once per 3 months, once per \> 3 months and others
Time frame: 3 years
To investigate the risk factors associated with crude mortality on HD facility level
Examine the association of risk factors back to 3 years ago to crude mortality on HD facility level, risk factors back to 3 years ago including: Constitution ratio of different sK levels after LIDI in ranges: (0, 3.5\], (3.5, 5.0\], (5.0, 5.5\], (5.5, 6.0\], (6.0, 6.5\], (6.5, 7.0\], (7.0\~) mmol/L in HD centers back to 3 years ago. Constitution ratio of last sK levels before death in ranges: (0, 3.5\], (3.5, 5.0\], (5.0, 5.5\], (5.5, 6.0\], (6.0, 6.5\], (6.5, 7.0\], (7.0\~) mmol/L in HD centers Key sK management factors (dialysis frequency, dialysate potassium concentration, sK testing frequency) Other factors (length of dialysis/session, patients dialysis vintage, residual renal function, etiology of ESRD, comorbidities, medication use)
Time frame: 3 years
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