Clinical Observation on Kuntai Capsule in Treating Early-onset Ovarian Hypofunction

Inclusion Criteria: 1. The women aged \<40 years old. 2. Serum basal follicle stimulating hormone (FSH) level ≥15 IU/L at least twice inspection (two occasions \>4 weeks apart). Rare menstruation or menopause for at least 4 months. 3. Individuals meeting the above criteria who voluntarily consented to study participation. Exclusion Criteria: 1. Pregnant and lactating patients; 2. Patients with endometriosis, adenomyosis, endometrial lesions (submucous fibroids, endometrial polyps, etc.), hysteromyoma \> 4cm or hysterectomy; 3. Patients with known or suspected breast cancer history and estrogen-dependent malignant tumor; 4. Patients with personal history of venous thromboembolism (VTE) or high risk of VTE (including body mass index \> 30 kg/m2, smoking and family history of thrombosis); 5. Patients with porphyria; 6. Patients with serious primary diseases or mental illness such as cardiovascular, liver, kidney and hematopoietic system; 7. Patients who are participating in other clinical trials or have participated in other clinical trials in the past three months; 8. Patients who suspect or have a history of alcohol and drug abuse; 9. Patients who are known to be allergic to the test drugs or their components; 10. The researchers determined that patients are not suitable for this trial.