Polyglucosamine L112 in Overweight and Obese Subjects

Inclusion Criteria: * weight \> 75 Kg * absence of previous diet therapy attempts * no fluctuation of at least 3 kg in the previous 3 months * Beck Depression Inventory score \< 20 pt * Binge Eating Scale score \< 27 pt Exclusion Criteria: * allergy to shellfish * pregnancy or breast feeding * presence of cardiopathies, nephropathies, liver diseases, bronchopneumopathies, haemopathies, dermopathies, chronic-degenerative diseases of the Central Nervous System * presence of active peptic ulcer, ulcerative colitis, Crohn's disease, celiac disease, inflammatory bowel disease * symptomatic cholelithiasis * previous or current neoplasms * epilepsy * obesity secondary to endocrinopathies or genetic syndromes * significant motor disability or mental retardation * major depressive disorder, bulimia, panic disorder, obsessive-compulsive disorder, post-traumatic stress disorder, bipolar disorder (I or II), schizophrenia * previous history or current diagnosis of drug abuse or alcoholism * changing in smoking habits or quitting smoking in the last 6 months * current use or in the last 3 months of psychoactive drugs or current use or in the last 12 months of drugs affecting body weight or appetite