Prospective, nonrandomized, single-center, comparative study to define if right ventricular (RV) contractile reserve assessed by exercise CMR helps to improve the differential diagnosis between pathological and physiological remodeling of the RV; ie. arrhythmogenic right ventricular cardiomyopathy (ARVC) and athlete's heart.
Comparison of the RV contractile reserve in 4 groups of patients: Arrhythmogenic right ventricular cardiomyopathy (ARVC) patients; endurance athletes with a dilated RV, endurance athletes with normal RV, untrained subject with normal RV. Patients will come to the hospital for 3 visits (3 half days): * Visit 1: clinical evaluation, rest ECG, rest echocardiography, cardio-pulmonary exercise test. * Visit 2: exercise echocardiography, holter ECG monitor (48 yours) * Visit 3: rest CMR and exercise CMR (ergocycle)
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Enrollment
60
Rest ECG, rest echocardiography, cardio-pulmonary exercise test, exercise echocardiography, holter ECG monitor (48 yours), rest CMR, exercise CMR (ergocycle)
CHU Rennes
Rennes, France
RECRUITINGEvolution of right ventricular ejection fraction (RVEF) assessed with CMR during exercise
Time frame: Through study completion, an average of 1 month
Evolution of Tricuspid annular plane systolic excursion (TAPSE) during exercise
Time frame: Through study completion, an average of 1 month
Evolution of S' tricuspid wave during exercise
Time frame: Through study completion, an average of 1 month
Evolution of RV fractional area during exercise
Time frame: Through study completion, an average of 1 month
Evolution of free wall RV strain during exercise
Time frame: Through study completion, an average of 1 month
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.