The repercussions of the hormonal status of high-level sportswomen on their performance and health as well as on the Athlete's Biological Passport (ABP) have been little studied and remain poorly known. The investigators therefore propose to contribute to the improvement of current knowledge by determining, thanks to the implementation of a multidisciplinary monitoring, with the use of various tests and matrices, in female elite athletes and recreational athletes (control group): * 1\) the impact of cycle phase, absence of cycle or contraceptive use on physical and psychological performance, health as well as on ABP; * 2\) the potential confounding effects of the athlete's environment * 3\) correlations between the different matrices analyzed
Volunteers to be studied: 80 healthy female subjects (16 to 30 years old), divided into 2 groups: Group 1: 60 athletes, from different sports disciplines, in amenorrhea, with menstrual cycle or taking contraceptives Group 2: 20 leisure sports subjects with menstrual cycle or taking contraceptives Following the oral and written information of the project, the subjects have a minimum of 15 days of reflection before signing the written consent form. They will have the possibility, at any time, to voluntarily interrupt the study without having to justify themselves. Investigations to be performed: 1. Annual complete clinical examination : 2. "Out-of-competition" follow-up, time frame 6 months * medical, nutritional and respiratory monitoring * biological monitoring * psychological monitoring * performance monitoring 3. Non-invasive "in-competition" monitoring, only for Group 1, once in a year on the day before/after a major competition: * biological monitoring * psychological monitoring * performance monitoring (interview)
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
80
Multidisciplinary monitoring
Change from baseline weight
in kg, by impedancemeter
Time frame: 6 months
Change from baseline fat and lean mass
in kg, by impedancemeter
Time frame: 6 months
Change from baseline height
in cm, by height gauge
Time frame: 6 months
Change from baseline sex and stress hormones
concentration of oestradiol, progesterone, testosterone, DHEA, cortisol, LH and FSH in mol/L
Time frame: 6 months
Change from baseline food intake
food intake questionnaire to complete over 3 days, expressed in kcal/day
Time frame: 6 months
Change from baseline metabolic parameters
concentration of blood glucose, blood lactate, lipid profile, insulin, GH, IGF1, T3, IgA, PRL and leptin in mol/L
Time frame: 6 months
Change from baseline respiratory parameters
measure of FEV1 (forced expiratory volume in 1 second), expressed in % of vital capacity
Time frame: 6 months
Change from baseline inflammatory parameters
concentration of cytokines (TNF-alpha, IL-6) in mol/L
Time frame: 6 months
Change from baseline executive function
assessed by instability via static and dynamic postures (eyes open/closed) on platform
Time frame: 6 months
Change from baseline visual-spatial processing
3 D mental rotation test, assessed by scores: range from 0 - 24, with 24 representing a perfect total score
Time frame: 6 months
Change from baseline attention and working memory
Stroop Color Word Task, assessed by scores : range of interference from -15 - +15, with higher scores representing decreased selective attention
Time frame: 6 months
Change from baseline performance monitoring
field performance test, performance expressed in time
Time frame: 6 months
Change from baseline Athlete Biological Passport (Group 2)
assessed by analysis of the standardized parameters of the Athlete Biological Passport (WADA)
Time frame: 6 months
Change from baseline affects (Group 2)
Positive Affect and Negative Affect Schedule (PANAS), assessed by scores. Positive Affect Score: range from 10 - 50, with higher scores representing higher levels of positive affect. Negative Affect Score: range from 10 - 50, with lower scores representing lower levels of negative affect.
Time frame: 6 months
Change from baseline anxiety (Group 2)
Spielberger State-Trait Anxiety Inventory, assessed by scores: range from 20 - 80, with higher scores representing higher anxiety
Time frame: 6 months
Change from baseline Athlete Biological Passport (Group 1)
assessed by analysis of the standardized parameters of the Athlete Biological Passport (WADA)
Time frame: 8 months
Change from baseline affects (Group 1)
Positive Affect and Negative Affect Schedule (PANAS), assessed by scores. Positive Affect Score: range from 10 - 50, with higher scores representing higher levels of positive affect. Negative Affect Score: range from 10 - 50, with lower scores representing lower levels of negative affect.
Time frame: 8 months
Change from baseline anxiety (Group 1)
Spielberger State-Trait Anxiety Inventory, assessed by scores: range from 20 - 80, with higher scores representing higher anxiety
Time frame: 8 months
Interview (Group 1)
Self-confrontation interview for questioning the action
Time frame: 8 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.