To conduct a retrospective multicenter cohort study to define benchmark values for best achievable outcomes following microsurgical clipping of unruptured intracranial aneurysms (UIA).
Surgeons strive for the best possible outcome of their surgeries with the greatest possible chance for recovery of the patients. Therefore, monitoring and quality improvement is increasingly important in surgery. For this purpose, different concepts were developed with the aim to assess best achievable results for several surgical procedures and reduce unwarranted variation between different centers. The concept of a benchmark establishes reference values which represents the best possible outcome of high-volume centers and can be used for comparison and improvement. In the past years, the concept of benchmarking attaches greater importance in the field of healthcare, especially in surgery. Benchmark values are established within a patients' cohort for which the best possible outcome can be expected. The aim of our study is the establishment of robust and standardized outcome references after microsurgical clipping of unruptured intracranial aneurysms. After successful implementation of benchmarks from an international cohort of renowned centers, these data serve as reference values for the evaluation of novel surgical techniques and comparisons among centers or future clinical trials.
Study Type
OBSERVATIONAL
Enrollment
3,000
Microsurgical Clipping of Unruptured Intracranial Aneurysm
University Medical Center Hamburg-Eppendorf
Hamburg, Germany
RECRUITINGComplete occlusion of aneurysm
Aneurysm remnant in CT scan or angiography
Time frame: up to 6 months
Retreatment of aneurysm
Necessity of retreatment in endovascular or microsurgical technique
Time frame: up to 6 months
Mortality
Death of the patient
Time frame: up to 6 months
Chronic subdural hematoma
Development of chronic subdural hepatoma requiring intervention
Time frame: up to 6 months
Stroke
Occurrence of ischemic stroke
Time frame: up to 6 months
Cerebral vasospasm
Occurrence of cerebral vasospasm
Time frame: up to 6 months
Intracerebal haemorrhage
Occurrence of intracerebral haemorrhage related to aneurysm treatment
Time frame: up to 6 months
New neurological deficit
None, motor deficit, sensory deficit, aphasie
Time frame: up to 6 months
Modified Rankin Score
Difference of mRS compared to preoperative status
Time frame: up to 6 months
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Glasgow Outcome Scale
From 1 (death) to 5 (low disability)
Time frame: up to 6 months