Integrative Nutrition Care Plan for the Patient With Liver and Colorectal Cancer

Taipei Medical University66 enrolled

Overview

At present, the families of cancer patients are lack knowledge and experience of nutritional care after discharge. As a result, cancer patients often suffer from low nutritional status after being discharged from the hospital.

This study intends to design a home nutrition care plan to explore the effect of a home nutrition care plan on the nutritional status of patients with liver cancer and colorectal cancer at risk of malnutrition. Malnutrition or side effects often lead to natural food intake for patients. It is not enough to meet the nutritional requirements, so it is matched with dietary products to help patients more easily meet their nutritional requirements. Supplements are used to alleviate patients' side effects. It is hoped that they can help patients improve their nutritional status.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Malnutrition Cancer of Colon Cancer of Liver Nutrition Aspect of Cancer

Interventions

Nutritional consultantBEHAVIORAL

The control group is to be consulted by the dietitian using communication software (Line) or telephone to evaluate the nutritional requirement and guide the cancer diet principles before starting the project.

Nutritional consultant + High-calorie, high-protein liquid nutrition supplementDIETARY_SUPPLEMENT

Nutritional consultant + Liquid supplement + Powdered supplement 1 and 2

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with liver cancer or colorectal cancer stage I to III 2. Not suffering from other carcinomas in situ at the same time 3. Will undergo surgery or non-surgical cancer treatment 4. Can move, read and answer questions by itself 5. At least one social support (family or friend) to assist and support the patient to complete the trial 6. According to the aPG-SGA, the assessment score is between 4 \~ 9 7. The patient or caregiver can cooperate with the dietitian to track and answer related questions asked by the dietitian in a remote way through communication software or telephone every week. 8. Able to adjust diet or take nutrition and supplements daily with the guidance of a nutritionist 9. Be able to cooperate with doctors and the beginning of the study and monthly return visits and blood tests for health insurance items Exclusion Criteria: 1. Perform organ transplantation or palliative care 2. Hepatic encephalopathy 3. History of cardiovascular and cerebrovascular diseases 4. Severe organ failure of the heart, breathing, or kidneys 5. History of digestive tract inflammation or ulcer 6. Severe mental illness 7. An active infectious diseases 8. Those who can only use intravenous nutrition and cannot use enteral nutrition 9. People who are allergic to product ingredients (milk, soy, or mango and their products) 10. Unwilling to cooperate with dietitians to make dietary adjustments or supplement nutrition and supplements 11. Unwilling to actively treat cancer

Locations (1)

Taipei Medical University

Taipei, Taiwan

Outcomes

Primary Outcomes

Evaluate nutritional status indicators change

Improvement of nutritional status indicators: Abridged Patient-Generated Subjective Global Assessment (aPG-SGA) assessment scores.

Time frame: Baseline and at 0.5th month

Evaluate nutritional status indicators change

Improvement of nutritional status indicators: Abridged Patient-Generated Subjective Global Assessment (aPG-SGA) assessment scores.

Time frame: Baseline and at 1st month

Evaluate nutritional status indicators change

Improvement of nutritional status indicators: Abridged Patient-Generated Subjective Global Assessment (aPG-SGA) assessment scores.

Time frame: Baseline and at 1.5th month

Evaluate nutritional status indicators change

Improvement of nutritional status indicators: Abridged Patient-Generated Subjective Global Assessment (aPG-SGA) assessment scores.

Time frame: Baseline and at 2nd month

Evaluate nutritional status indicators change

Improvement of nutritional status indicators: Abridged Patient-Generated Subjective Global Assessment (aPG-SGA) assessment scores.

Time frame: Baseline and at 2.5th month

Evaluate nutritional status indicators change

Improvement of nutritional status indicators: Abridged Patient-Generated Subjective Global Assessment (aPG-SGA) assessment scores.

Time frame: Baseline and at third month

Secondary Outcomes

Evaluate anthropometric measurements change-Body weight

Data from ClinicalTrials.gov

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At the beginning of the plan, the dietitian first calculates the patient's daily calorie intake and the ratio of the three macronutrients and guides the patients or their family members of the nutritional care plan group B to implement a daily diet with a concentrated high-calorie and high-protein liquid supplement (Commercial formula contains 425 kcal and 19.1 grams of protein). Meanwhile, nutrition care plan group B will be given powdered supplement 1 (containing β-glucan and gamma-aminobutyric acid) and nutritional products and powdered supplement 2 (contains water-soluble dietary fiber and probiotics).

Time frame: Baseline and at 0.5th, 1st, 1.5th, 2nd, 2.5th, and third month

Evaluate anthropometric measurements change-Body mass index(BMI)

Weight and height will be combined to report BMI in kg/m\^2

Time frame: Baseline and at 0.5th, 1st, 1.5th, 2nd, 2.5th, and third month

Evaluate biochemical data change-White blood cells (WBC)

White blood cells (x10\^3/ul)