Evaluation of the Benefit of Non-opioid General Anaesthesia on Postoperative Pain in Laparoscopic Colonic Surgery

GCS Ramsay Santé pour l'Enseignement et la Recherche160 enrolled

Overview

Evaluation of the benefit of non-opioid general anaesthesia on postoperative pain in laparoscopic colonic surgery

Single-centre prospective randomised study carried out in two parallel groups of patients undergoing laparoscopic colectomy. * Group 1: conventional general anaesthesia with morphine * Group 2: general anaesthesia without opiates

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

160

Conditions

Colectomy

Interventions

anaesthesia without opiatesDRUG

Anaesthesia without opiates for patients undergoing laparoscopic colectomy

anaesthesia with morphineDRUG

anaesthesia with morphine for patients undergoing laparoscopic colectomy

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient over 18 years of age who has read and signed the consent form for participation in the study * Patient candidate for laparoscopic colectomy (planned or emergency) with possible conversion to laparotomy Exclusion Criteria: * Severe renal failure with baseline clearance\<30, hepatic failure with baseline PT\<40%, cardiac failure with LVEF\<20%. * Patient under court protection, guardianship or curatorship * Pregnant or breastfeeding patient * Patient not affiliated to the French social security system * Impossible to give the subject informed information and/or to give written informed consent: dementia, psychosis, disturbed consciousness, non-French speaking patient * Contraindication to anaesthesia or to the administration of one of the products used in the anaesthesia protocol * Patient participating in another interventional research or in a period of exclusion from a previous research

Locations (1)

Hôpital Privé Médipôle

Villeurbanne, France

Outcomes

Primary Outcomes

Morphine Use

All intravenous and oral morphine consumed in the first 48 hours after surgery

Time frame: 48 hours