Opioid Free Anesthesia in Maxillofacial Surgery

Université NAZI BONI66 enrolled

Overview

Opioid free anesthesia is a promising practice in anesthesia. Studies already carried out have compared OFA to an opioid or "opioid anesthesia" (OA) protocol without the use of antihyperalgesic in the OA protocol. Most of the studies currently available have been carried out in Europe, America and a few in Asia under conditions other than those available in precarious situations.That's why we decide to conduct a study to evaluate the effectiveness of an OFA protocol in maxillofacial surgery in Burkina Faso.

The patients were recruited at the University Hospital of Souro Sanou in Bobo Dioulasso

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Maxillofacial Surgery

Interventions

opioid free anesthesiaOTHER

Maintenance of anesthesia was done with halothane. The incision was allowed at 1.2 MAC of halothane. This halogen was administered according to the hemodynamic parameters and the habits of the anesthesia team. Before waking up, all the patients benefited from preventive analgesia with 1 g paracetamol combined with 20 mg nefopam by slow intravenous injection over approximately 15 minutes.

Eligibility

Sex: ALLMin age: 15 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients aged between 15 and 65 years, admitted to the central operating room of the hospital for maxillofacial surgery. Exclusion Criteria: * Known or suspected coronary artery disease on preoperative consultation; * Unstable arterial hypertension * Insulin-dependent diabetes * Second degree atrioventricular block * Neuro-vegetative dysautonomia; * known allergy or intolerance to a drug of the protocols

Locations (1)

Guibla

Bobo-Dioulasso, Houet, Burkina Faso

Outcomes

Primary Outcomes

Highest numerical pain score

The main highest numerical pain score postoperatively

Time frame: First two hours postoperatively

Secondary Outcomes

Blood pressure

Changes in blood pressure

Time frame: six minutes after incision

Ephedrine

Intraoperative consumption of ephedrine

Time frame: During anesthesia

Wake up

wake up time

Time frame: Time between the end of surgery and extubation

Nausea-Vomiting

The proportion of nausea-vomiting after surgery

Time frame: During 24 after surgery

Highest numerical pain score 24 hours

The mean of the highest EN score during the first 24 hours postoperatively

Time frame: The first 24 hours postoperatively

Non-surgical complications

The proportion of non-surgical complications within 24 hours of anesthesia

Time frame: During 24 hours after surgery

Heart rate

Changes in heart rate

Time frame: six minutes after incision

Data from ClinicalTrials.gov

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