Medical Expulsive Therapy Post-SWL For Renal Stones

Mansoura University235 enrolled

Overview

To evaluate the efficacy and stone free rate of placebo versus tamsulosin as medical expulsive therapy post-SWL in patients with renal stone less than 20 mm

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

235

Conditions

Urologic Diseases Urolithiasis Stone, Kidney

Interventions

TamsulosinDRUG

Tamsulosin 0.4 mg once daily

PlaceboDRUG

Placebo once daily

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Renal stone ≤ 20 mm. * Lower calyceal stone ≤ 15 mm Exclusion Criteria: * Women with known or suspected pregnancy or breastfeeding. * History of alpa-blockers (more than 7 days prior to study participation) * History of ureteral stricture * Multiple (that is more than 2) stones * Stone in solitary kidney (either anatomically or functionally). * Presence of urinary sepsis. * Estimated glomerular filtration rate \< 30 ml/min * Contraindication or allergy to tamsulosin

Locations (1)

Urology and Nephrology Center

Al Mansurah, Aldakahlia, Egypt

Outcomes

Primary Outcomes

Stone free rate defined as patient free of any stone residual

assessed by Non-contrast Computed Tomography of Urinary Tract (NCCT-UT)

Time frame: at 3 months

Data from ClinicalTrials.gov

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