This study will investigate the effects of post moderate intensity aerobic exercise hot water immersion on physiological and perceptual responses in physically inactive middle-aged adults when compared to moderate intensity aerobic exercise and hot water immersion alone.
A large number of middle aged adults do not achieve the minimum recommended amount of physical activity. This consequently increases the risk of cardiovascular disease and all-cause mortality. Although below the recommended physical activity guidelines, it is important to highlight that a considerable proportion of these individuals do take part in some form of physical activity within their weekly routines. Hence, identifying complementary therapies that can enhance the health benefits from smaller amounts of exercise are of great value for many physically inactive middle-aged adults. An in increase in body temperature from a single session of passive heating has been shown to mimic many of the beneficial physiological responses of exercise, such as, an increase in heart rate, skin blood flow and an increase in circulating angiogenic factors. However, lab based studies often push participants to the limit of thermal tolerance which may reduce long term adherence in the real world. Therefore, this study will investigate whether the use of post exercise hot water immersion can prolong and / or intensify exercise mediated physiological responses that underpin health benefits, whilst also assessing the perceptual responses, in comparison to exercise and hot water immersion alone. Through the use of a repeated measures design, participants will randomly take part in three conditions; 1) post exercise hot water immersion (30 minutes of moderate intensity cycling followed by 10 minutes of supine rest and 30 minutes of whole body hot water immersion at 40°C); 2) aerobic exercise (30 minutes of moderate intensity cycling followed by 10 minutes of supine rest and 30 minutes of seated rest at room temperature); 3) hot water immersion condition (30 minutes of whole body hot water immersion at 40°C followed by 10 minutes of supine rest and 30 minutes of whole body hot water immersion at 40°C). Each condition will be separated by a minimum of 1-week. Outcome measures will either be assessed at regular intervals or at 0, 30, 70 and 100 minute time points for each condition.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
16
Participants will complete 30 minutes of cycling on a lode bicycle ergometer (50% of VO2max), followed by a 10-minute transfer period and then 30 minutes of whole-body hot water immersion in a hot tub (water temperature 40°C).
Participants will complete 30 minutes of cycling on a lode bicycle ergometer (50% of VO2max).
Participants will complete 30 minutes of whole-body hot water immersion in a hot tub (water temperature 40°C), followed by a 10-minute transfer period and then an additional 30 minutes of whole-body hot water immersion in a hot tub (water temperature 40°C).
Coventry University
Coventry, West Midlands, United Kingdom
Change in circulating plasma nitrite (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in brachial artery total shear rate (S-1)
Terason ultrasound recording of the brachial and superficial femoral artery
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in brachial artery antegrade shear rate (S-1)
Terason ultrasound recording of the brachial and superficial femoral artery.
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in brachial artery retrograde shear rate (S-1)
Terason ultrasound recording of the brachial and superficial femoral artery
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in brachial artery diameter (mm)
Terason ultrasound recording of the brachial and superficial femoral artery
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in brachial artery blood flow (ml/min)
Terason ultrasound recording of the brachial and superficial femoral artery.
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in brachial artery compliance (μm/mmHg)
Terason ultrasound recording of the brachial artery. Brachial artery compliance will be calculated by using the change in blood volume and blood pressure
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in systolic blood pressure (mmHg)
Measured using an automated blood pressure cuff
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Time frame: Measurements taken at 10 minute intervals up to 100 minutes
Change in diastolic blood pressure (mmHg)
Measured using an automated blood pressure cuff
Time frame: Measurements taken at 10 minute intervals up to 100 minutes
Change in mean arterial pressure (mmHg)
Measured using an automated blood pressure cuff. Mean arterial pressure will be calculated by using systolic and diastolic blood pressure
Time frame: Measurements taken at 10 minute intervals up to 100 minutes
Change in pulse pressure (mmHg)
Measured using an automated blood pressure cuff. Pulse pressure will be calculated using systolic and diastolic blood pressure
Time frame: Measurements taken at 10 minute intervals up to 100 minutes
Change in circulating serum Interleukin-6 (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in circulating serum Interleukin-10 (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in circulating serum Interleukin-8 (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in circulating serum Interleukin-1Ra (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in circulating serum Vascular endothelial growth factor (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in circulating serum Endothelin-1 (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Circulating serum Monocyte chemoattractant protein-1 (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in circulating serum Matrix metallopeptidase-2 (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Change in circulating serum Matrix metallopeptidase-9 (pg/ml)
Venous blood sample
Time frame: Measured at 0, 30, 70 and 100 minutes
Energy expenditure (kcal/h-1)
Measured initially by breath by breath analysis through the use of a Ultima and calculated via indirect calorimetry
Time frame: Gas measurements taken continually up to 70 minutes. Energy expenditure calculated from the 30 minutes of exercise, hot water immersion and/or rest periods.
Change in thermal comfort
Thermal comfort Likert scale from a positive score of +5 very comfortable (maximum) to a negative score of -5 very uncomfortable (minimum)
Time frame: Measured at 10 minute intervals up to 100 minutes
Change in thermal sensation
Thermal sensation Likert scale from +5 (maximum) hot to -5 cold (minimum)
Time frame: Measured at 10 minute intervals up to 100 minutes
Change in basic affect
Basic affect Likert scale from a positive score of +5 very good (maximum) to a negative score of -5 very bad (minimum)
Time frame: Measured at 10 minute intervals up to 100 minutes
Change in physical activity enjoyment scale
Feelings about exercise and / or passive heating on a Likert scale from a positive score of 1 (maximum) to a negative score of 7 (minimum)
Time frame: Measured ~12 minutes post intervention