Efficacy and Safety of Ciprofol Compared to Propofol for Nonintubated General Anesthesia in Patients Undergoing TAVR

Inclusion Criteria: * Patient scheduled for TAVR through femoral artery access * 1h ≤ Expected duration of surgery ≤ 3h * Planned for general anesthesia without intubation * 18 ≤ BMI ≤ 30 * ASA category Ⅱ～Ⅳ Exclusion Criteria: * Contraindications to anesthesia/sedation or a history of adverse reaction to anesthesia/sedation * Known allergies to eggs, soy products, opioids and their antidotes, propofol, etc; Contraindications of propofol, opioids and their antidotes * Shock and hypotension difficult that is to be corrected by vasoactive drugs in the screening period * Hemoglobin (HB) \< 10.0 g / dl (100 g / L) * Judged by the investigator to have any other factors that make the subject unsuitable for participation in the study.