The purpose of this study is to observe the relationship between the changes of circulating exosomes and the development and outcome of the disease in patients with intracerebral hemorrhage, and to search for early serum markers and potential intervention targets for disease monitoring in patients with intracerebral hemorrhage
Study Type
OBSERVATIONAL
Enrollment
300
Tandu Hospital, Fourth Military Medical University
Xi'an, China
RECRUITINGThe type and content of circulating exosomes
After the exosomes were isolated, RNA sequencing and proteome sequencing were performed to identify the change of circulating exosomes
Time frame: within 24 hours of ICH
Modified Rankin scale (mRS) scores
mRS scores was divided into seven grades (0-6). The higher the score, the more severe the symptoms
Time frame: from onset to three months or six months
mortality
Time frame: through study completion,an average of 1 year
hospital stay
Time frame: From hospitalization to discharge,up to one month
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