during PCNL; A few milliliters of nor-epinephrine is injected into the intended tract after puncture of pelvicalyceal system and before its dilatation compared to injection of saline (placebo). hemoglobin change \& blood loss is estimated and will compared.
All patients of are positioned in lithotomy position and 6 F open tip ureteral catheter is fixed by cystoscope. Then, A pelvicalyceal system is punctured under ultrasound and/or fluoroscopic guidance, then a 18 Gauge (G) puncture needle is introduced toward the desired calyx and a 0.038 inch guide wire is inserted. then 20 G Chiba needle is introduced alongside the puncture needle for infiltration of the whole tract by either a few milliliters of nor-epinephrine or saline. then, the tract is dilated over the guide wire, lastly an Amplatz sheath was inserted. nephroscope is used for stones disintegration by pneumatic or laser lithotripter . Fragments are washed out or removed by forceps.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
140
The PCNL tract is infiltrated by Nor-Epinephrine or Normal Saline before its dilatation.
Banha University Hospitals
Banhā, Kalubiaya, Egypt
Banha university hospital
Banhā, Qalyubia Governorate, Egypt
hemoglobin drop
the lower drop is better
Time frame: 72 hours post intervention
blood loss
the lower loss is better
Time frame: immediately after surgery
stone free rate
the higher is better
Time frame: within 3 months post-operative
adverse events
the lower is better
Time frame: within 30 days post-operative
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