Review the data of patients who underwent coronary artery bypass grafting (CABG) at the Department of Cardiovascular Surgery in Ruijin hospital from March 2020 to May 2022, including medical history, head and neck CTA, head CT scan, and early postoperative (within 7 days after surgery) neurological complications (defined as a composite of stroke, delayed awakening and severe delirium) . Case-control and retrospective cohorts were built to explore risk factors of early postoperative neurological complications, And its association with baseline carotid-cerebral vascular disease. Describe the epidemiological data of early postoperative neurological complications (stroke, delayed awakening, and severe delirium) after CABG surgery (within 7 days after surgery); explore independent risk factors of compound neurological complications, build predictive models; compare the effects of carotid-cerebral artery disease on early postoperative compound neurological complications.
Study Type
OBSERVATIONAL
Enrollment
1,002
Ruijin Hospital Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China
the incidence of 7-day neurological complications
a composite of stroke, delayed awakening, severe delirium
Time frame: within 7 days post-CABG
the incidence of 7-day stroke
including cerebral infarction, cerebral hemorrhage, and hypoxic-ischemic encephalopathy
Time frame: within 7 days post-CABG
the incidence of delayed awakening
post-surgery patient does not wake up at 48 hours after withdrawing sedative
Time frame: within 48 hours post-CABG
the incidence of severe delirium
ICU CAM-II score≥2 points
Time frame: within 7 days post-CABG
the incidence of All-cause death
Death from any cause
Time frame: 7 days, 30 days and 1 year post-CABG
the incidence of CV-death
Including death resulting from an acute myocardial infarction , sudden cardiac death, death due to heart failure, death due to stroke, death due to cardiovascular procedures, death due to cardiovascular hemorrhage, and death due to other cardiovascular causes
Time frame: 7 days, 30 days and 1 year post-CABG
the incidence of myocardial infraction
According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including CABG-related MI, non CABG-related MI, silent MI and unknown type.
Time frame: 7 days, 30 days and 1 year post-CABG
the incidence of repeat revascularization
any PCI and CABG.
Time frame: 7 days, 30 days and 1 year post-CABG
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