Estimating Blood [Lactate] Non-Invasively

N/AWithdrawnNCT05036122

Mayo Clinic

Overview

The purpose of this study is to validate the LabClasp's ability to estimate blood \[lactate\].

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Conditions

Healthy

Interventions

LabClaspDEVICE

Non-invasive device that estimates blood \[lactate\] from interstitial fluid via a proprietary algorithm. The device is placed between the first and second knuckle of a finger and gently applies slight pressure to extract interstitial fluid from the skin. Sensors within the device quickly estimate blood \[lactate\] and return a value to the subject via an accompanying tablet within 20 seconds.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria - Aim 1: * Subjects must be able to provide written consent. * Adults 18 years of age and older. * Nonsmokers. * No recent hospitalization (\< 60 days). * Ability to perform high-intensity exercise. Inclusion Criteria - Aim 2: * Subjects must be able to provide written consent to be included in the research study. * Adults 18 years of age and older. * Nonsmokers. * Current ICU patient. * Have regular blood samples taken for \[lactate\] measurements. * Have one or more risk factors for sepsis. Exclusion Criteria - Aims 1 and 2: * History of, or active malignancy. * History of HIV with antiretroviral treatment. * Smokers. * Pregnancy.

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Outcomes

Primary Outcomes

Blood [lactate] during incremental exercise

Measured via venous blood and the LabClasp

Time frame: 1 day

Blood [lactate] measurements in ICU patients

Measured via venous blood and the LabClasp

Time frame: 1 day

Data from ClinicalTrials.gov

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