This study aimed to survey the growth of children who were on elimination diet due to cow milk allergy in Turkey. 0-5 year aged children diagnosed with cow's milk allergy (CMA) and healthy age-sex-matched children as the control group was planned for inclusion. Participants will be included in the study by consecutive sampling. The anthropometry measurements (height-for-age \[HFA\], weight-for-age \[WFA\], and weight-for-height \[WtHt\]) will be evaluated according to the Z-score using the WHO ANTHRO \[Z-score = Patient's value - Average value / Standard Deviation (SD)\]. The Z-score (SDS) in the average child by age was "0".
0-5 year aged children diagnosed with cow's milk allergy (CMA) and healthy age-sex-matched children as the control group was planned for inclusion. The study will constitute of two groups; group 1; the children who received cow's milk elimination (CME) diet and group 2; the healthy controls. Group 1 will constitute of children aged 0-5 years who received a CME diet due to CMA (Ig E-mediated and/or non-Ig E-mediated and/or mixed type)\], confirmed by an oral food challenge test (OFC) and had reintroduced cow's milk for at least ≥ three months ago. Participants will be included in the study by consecutive sampling. The anthropometric measurements (height-for-age \[HFA\], weight-for-age \[WFA\], and weight-for-height \[WtHt\]) will be evaluated according to the Z-score using the WHO ANTHRO \[Z-score = Patient's value - Average value / Standard Deviation (SD)\]. The Z-score (SDS) in the average child by age was "0".
Study Type
OBSERVATIONAL
Enrollment
100
University of Health Sciences, Gulhane Education and Research Hospital
Ankara, Turkey (Türkiye)
RECRUITINGBody weight in kilograms-T0
Body weight (kg)
Time frame: One month prior to the diagnosis of CMA
Body weight in kilograms-T1
Body weight (kg)
Time frame: On the 3-month of CME diet
Body weight in kilograms-T2
Body weight (kg)
Time frame: Three months after the end of the CME diet
Body weight in kilograms-T3
Body weight (kg)
Time frame: The last examination date of the patient after 3rd month control after CME diet
Height in centimeters-T0
Height (cm)
Time frame: One month prior to the diagnosis of CMA
Height in centimeters-T1
Height (cm)
Time frame: On the 3-month of CME diet
Height in centimeters-T2
Height (cm)
Time frame: Three months after the end of the CME diet
Height in centimeters-T3
Height (cm)
Time frame: The last examination date of the patient after 3rd month control after CME diet
Head circumference in centimeters-T0
Head circumference (cm)
Time frame: One month prior to the diagnosis of CMA
Head circumference in centimeters-T1
Head circumference (cm)
Time frame: On the 3-month of CME diet
Head circumference in centimeters-T2
Head circumference (cm)
Time frame: Three months after the end of the CME diet
Head circumference in centimeters-T3
Head circumference (cm)
Time frame: The last examination date of the patient after 3rd month control after CME diet
Dietary intake
Three day dietary record
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Hemoglobin
Hemoglobin g/dl
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Sodium
sodium mg/ml
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Potassium
Potassium
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Albumin
Albumin
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Protein
Protein
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Calcium
Calcium
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Vitamin B12
Vitamin B12
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-selenium
Selenium
Time frame: The last examination date of the patient after 3rd month control after CME diet
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Blood measurements-zinc
Zinc
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-25-OH vitamin D
25-OH vitamin D
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-iron
Iron
Time frame: The last examination date of the patient after 3rd month control after CME diet
Blood measurements-Folate
Folate
Time frame: The last examination date of the patient after 3rd month control after CME diet