This study is designed to observe human consuming effect of a beauty drink powder and combined use with a cosmetic apparatus. It is a randomized, double-blind, and placebo-control study. The target enrollment of subjects is 160 and 4 arms are included, a placebo control, drink powder alone, cosmetic apparatus alone, and drink powder plus cosmetic apparatus. Effects on skin dullness, skin tone unevenness, skin dryness, skin elasticity, wrinkle and fine line are evaluated. Both objective and subjective methods are used for efficacy evaluation. Data are collected at baseline, week 4, week 8, and week 12 after treatment.
In this study, objective parameters are measured by the instruments as following: VisioScan VC20 is used for skin roughness and wrinkle assessment, chromameter CR-400 is used to assess skin color, skin gloss is assessed by Glossymeter, skin hydration is assessed by Corneometer, TEWL is assessed by Vapometer, and skin elasticity is assessed by Cutometer. VISIA-CR and VISIA-7 are used in skin radiation and wrinkle visualization. Clinical assessment is performed by expert visual grading on * Skin evenness * Skin radiance * Skin elasticity * Skin smoothness * Skin firmness * Skin moisture * Skin plumpness
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
160
Beauty drink powder is designed as a oral beauty product to provide benefits to skin
This device is designed to let participants to experience brighter, softer, smoother skin and an energizing facial massage. A synergestic effect when combine with beauty drink powder is expected.
Shanghai China-norm Quality Technical Service Co., Ltd.
Shanghai, Shanghai Municipality, China
Skin health (evenness)
Change from baseline in investigator facial grading of evenness (using scores from 0-10 to indicate skin evenness from evenness to unevenness) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin health (radiance)
Change from baseline in investigator facial grading of radiance (using scores from 0-10 to indicate skin radiance from radiance to dulness) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin health (elastisity)
Change from baseline in investigator facial grading of elastisity (using scores from 0-10 to indicate skin elasticity from elastic to nonelastic) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin health (smoothness)
Change from baseline in investigator facial grading of smoothness (using scores from 0-10 to indicate skin smoothness from smooth to rough) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin health (firmness)
Change from baseline in investigator facial grading of firmness (using scores from 0-10 to indicate skin firmness from firm to slack) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin health (moisture)
Change from baseline in investigator facial grading of moisture (using scores from 0-10 to indicate skin moisture from moist to dry) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin health (plumpness)
Change from baseline in investigator facial grading of plumness (using scores from 0-10 to indicate skin plumpness from plump to not plump) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin health (overall)
Change from baseline in investigator facial grading of overall (using scores from 0-10 to indicate overall skin health from good to worse) at days 28, 56, and 84 using Wilcoxon and Mann Whitney two tailed assessment for nonparametric data
Time frame: baseline, day 28, day 56, and day 84
Skin roughness and wrinkle of face determined by VisioScan VC20
Change from baseline in skin roughness and wrinkle at days 28, 56, and 84 using Wilcoxon and Mann-Whitney test for nonparametric data
Time frame: Baseline, day 28, day 56, and day 84
Skin Color of L, a, b and ITA value of face determined by chromameter
Change from baseline in skin color of L, a, b, and ITA value at days 28, 56, and 84 using Wilcoxon and Mann-Whitney test for nonparametric data
Time frame: Baseline, day 28, day 56, and day 84
Skin Glossiness of face determined by Glossymeter
Change from baseline in skin glossiness at days 28, 56, and 84 using Wilcoxon and Mann-Whitney test for nonparametric data
Time frame: Baseline, day 28, day 56, and day 84
Skin hydration of face determined by Corneometer
Change from baseline in skin hydration at days 28, 56, and 84 using Wilcoxon and Mann-Whitney test for nonparametric data
Time frame: Baseline, day 28, day 56, and day 84
Face TEWL determined by Vapometer
Change from baseline in face TEWL at days 28, 56, and 84 using Wilcoxon and Mann-Whitney test for nonparametric data
Time frame: Baseline, day 28, day 56, and day 84
Skin elasticity of face determined by Cutometer
Change from baseline in skin elasticity at days 28, 56, and 84 using Wilcoxon and Mann-Whitney test for nonparametric data
Time frame: Baseline, day 28, day 56, and day 84
Skin radiance and lines assessed by facial photo capture using VISIA-CR and VISIA-7
Change from baseline in skin radiance and lines at days 28, 56, and 84 using Wilcoxon and Mann-Whitney test for nonparametric data
Time frame: Baseline, day 28, day 56, and day 84
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