The Impact of Remimazolam for Postoperative Sedation on the Left Ventricular Systolic Performance in Cardiac Surgery

Konkuk University Medical Center15 enrolled

Overview

This study analyzes the impact of intraoperative Remimazolam infusion for postoperative sedation on the left ventricular global longitude strain (LV-GLS) patients undergoing cardiac surgery

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Coronary Artery Disease

Interventions

Remimazolam Injection [Byfavo]DRUG

Remimazolam injection and continuous infusion for postoperative sedation, 0.2 mg/kg for 1 min and continuous infusion of 1-2 mg/kg/hour

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * elective off-pump coronary artery bypass surgery Exclusion Criteria: * arrhythmia * LV ejection fraction \< 50 % * preoperative inotropic support

Outcomes

Primary Outcomes

change of the left ventricular global longitudinal strain

mean values of the left ventricular global longitudinal strain after 3 minutes, 5 minutes and 10 minutes after the Remimazolam administration

Time frame: 1 minutes

Data from ClinicalTrials.gov

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