Probiotics as Adjunctive Migraine Prophylaxis

Inclusion Criteria: 1. Subjects fulfilling criteria for episodic migraine as per the Third Edition of The International Headache Society (ICHD-3) (Table 1) 2. Patients diagnosed with episodic migraine (4 or more episodes per month) for a minimum of 3 months. 3. On a steady treatment regimen: preventive and acute migraine medications and therapies unchanged over the last 3 months 4. Adult patients Age \> 18 years old 5. A signed and dated informed consent document indicating that the subject has been informed of all pertinent aspects of the study including any known and potential risks and available alternative treatments. Exclusion Criteria: 1. Lactose intolerance 2. Previous history of small and large bowel surgery 3. Use of probiotics or antibiotics in 2 weeks before baseline visit. 4. Patients with medical conditions such as severe hypertension, infections, 5. Malignancy, cardiovascular and cerebrovascular diseases, epilepsy, degenerative central nervous system diseases, renal failure, hepatic failure, bleeding diathesis and serious mental illnesses 6. Headache with red flags symptoms that may suggest organic secondary headaches. 7. Onset of headache more than 50 years 8. Prior GI infection in the previous 3-months 9. Morbid obesity (BMI \>40) 10. Pregnant or lactating women