The enhanced recovery anesthesia concept has been widely adopted, including cesarean delivery. Modern obstetrical anesthesia aims to offer an experience to a patient undergoing a cesarean delivery similar to normal vaginal delivery in order to maximize postoperative comfort and facilitate bonding between the mother and her newborn. Therefore, early removal of the bladder catheter has been recommended. However, this is challenged by the administration of intrathecal morphine recommended to provide long-lasting postoperative analgesia after cesarean delivery.
This double-blind, randomized trial investigates the effects of intrathecal morphine on urinary dynamics in women undergoing CD under spinal anesthesia. The hypothesis is that the addition of intrathecal morphine (ITM) will delay micturition in women undergoing cesarean delivery. The primary outcome is the effect of ITM on urodynamics the difference in time to micturition. The secondary outcome is the need for bladder re-catheterization.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
56
The effect of intrathecal morphine on vesical function and the need for bladder re-catheterization after a cesarean delivery
NaCl 0.9%
50 mg prilocaine + 2.5 mcg sufentanil
University of Liege, University Hospital
Liège, Belgium
First micturition (hours)
Vesicle function 1
Time frame: until the end of the study, an average of 6 months
Bladder volume (mL)
Vesicle function 2
Time frame: until the end of the study, an average of 6 months
Debimetry
Vesicle function 3
Time frame: until the end of the study, an average of 6 months
Bladder re-catherization
Vesicle function 4
Time frame: until the end of the study, an average of 6 months
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20 mL of ropicavaine 0.375% on each side