Long-term Results of Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults

Turku University Hospital17 enrolled

Overview

Long-term results of tonsillectomy in the treatment of obstructive sleep apnea in adults

The investigators are studying long-term efficiency of tonsillectomy in adults with obstructive sleep apnea caused by tonsillar hypertrophy. These patients have undergone tonsillectomy in 2004-2018 and now 3-17 years later investigators will perform new polysomnographies and compare these results with preoperative values. Especially the reduction in apnea-hypopnea index (AHI) will be evaluated. The quality of life and possible symptoms will be measured with questionnaires.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Obstructive Sleep Apnea Tonsillar Hypertrophy Sleep Apnea Syndromes

Interventions

PolysomnographyDEVICE

Polysomnography is performed one time overnight

Eligibility

Sex: ALLMin age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age at least 16 during tonsillectomy * preoperative obstructive sleep apnea and AHI (apnea-hypopnea index) \> 14 * tonsillectomy has been done because of the symptoms caused by tonsillar hypertrophy (ICD-10 diagnostic codes G47.3, R06.5 or J35.1) * in addition to tonsillectomy, patients may have undergone shortening of uvula and/or radio frequency ablation of soft palate Exclusion Criteria: * AHI \< 14 * in addition to tonsillectomy patient has undergone uvulectomy, uvulopalatoplasty, uvulopalatopharyngoplasty or mandibular advancement * other, evaluated by investigator

Locations (1)

Turku University Hospital

Turku, Southwest Finland, Finland

Outcomes

Primary Outcomes

Apnea-hypopnea index

Post-operative apnea-hypopnea index (AHI) reduction by 50% compared to preoperative values in polysomnography.

Time frame: 3-17 years

Secondary Outcomes

Quality of life measured by Glasgow Benefit Inventory (GBI)

General quality of life questionnaire. 18 questions, score 1-5 in each question, higher is better.

Time frame: 3-17 years

Quality of life measured by Epworth sleepiness scale (ESS)

Questions regarding sleepiness. Score 0-24, lower is better.

Time frame: 3-17 years

Apnea-index (AI)

Post-operative apnea index reduction compared to preoperative values in polysomnography.

Time frame: 3-17 years

Snoring time

Post-operative reduction of snoring time compared to preoperative values in polysomnography

Time frame: 3-17 years

Oxygen Desaturation Index (ODI)

Post-operative reduction of oxygen desaturation index compared to preoperative values in polysomnography

Time frame: 3-17 years

Data from ClinicalTrials.gov

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