The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes

Inclusion Criteria: * Leading a sedentary life * Those who have sufficient motivation to participate in the exercise program (will be evaluated by a one-on-one interview by the researchers) * Have the same weight for 6 months before participating in the study (±2.5 kg) * Those diagnosed with prediabetes by oral glucose tolerance test and/or HbA1c measurement Exclusion Criteria: * Serious medical condition (for example, advanced malignancy or major neurological, psychiatric or endocrine disease, respiratory failure, etc.) that would prevent the person from participating in exercise training. * Having cardiovascular disease * Being diabetic * Using metformin before participating in the study * Receiving hormone replacement therapy * Life expectancy less than 1 year * HIV positivity * Substance use * Functional dependency * Cognitive weakness * Those who have other diseases that will affect the results of the study (respiratory diseases, muscle diseases, etc.) * Those who use drugs or supplements that will affect the results of the study